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Methadone Vs. Buprenorphine: What Makes Them Different?

Methadone and buprenorphine are both effective medications used in the treatment of opioid dependency, but they work in different ways and have distinct characteristics. Understanding the differences between methadone versus buprenorphine can help individuals, in conjunction with their healthcare providers, make informed decisions about the best treatment options. At Crossroads, a specially trained clinical provider will work with you to determine the best course of treatment.

How Methadone Works

Methadone is a full opioid agonist. It binds to the same opioid receptors in the brain as other opioids, such as heroin, fentanyl or prescription painkillers, but in a controlled manner. This helps reduce withdrawal symptoms and cravings without causing the same intense high. Methadone is often used in opioid maintenance therapy to help individuals stabilize their lives and eliminate the use of illicit opioids.

How Buprenorphine Works

Buprenorphine is a partial opioid agonist. Unlike methadone, it activates opioid receptors but only partially. Buprenorphine helps alleviate withdrawal symptoms and cravings while minimizing the risk of overdose and misuse. It is often combined with naloxone in a formulation called SUBOXONE® to further reduce the risk of misuse.

Administration and Accessibility

Methadone is usually administered in specialized recovery clinics. Patients must visit these clinics daily or several times a week to receive their dose, although take-home doses may be provided for stable patients. Buprenorphine may also be given in this manner.

Buprenorphine can also be prescribed by certified providers and taken at home. This flexibility makes it more accessible and convenient for many patients. The ability to take medication at home can lead to greater adherence to treatment and more independence in managing recovery.

Effectiveness and Duration

Methadone has been used for decades and is well-established in opioid treatment programs. It is effective in reducing opioid cravings and withdrawal symptoms over long periods.

Buprenorphine, while newer, has also proven effective in managing opioid addiction. It offers a more flexible treatment option with its at-home administration. The medication has a long half-life, which means it can be taken less frequently than some other opioids.

Explore Your Treatment Options with Crossroads

If you’re considering methadone or buprenorphine for opioid dependency, Crossroads can provide expert guidance and personalized care. Our 100+ centers across 9 states provide the most convenient, comprehensive, high-quality care. Our team offers the full array of FDA-approved treatment medications and supports patients through treatment plans tailored to individual needs.

Accessing the right treatment has never been easier with same-day and virtual appointments available. Call or text 855.694.8288 today to start your journey toward recovery with the support of our experienced professionals. At Crossroads, we’re committed to helping you achieve lasting change and better health. Reach out now to find the treatment that’s right for you.